Scott R Mackenzie Foundation Inc | Foundation Profile
GrantBay analyzes IRS Form 990-PF data to help grant seekers find fit funders like Scott R Mackenzie Foundation Inc. Data shown is extracted from Form 990-PF filings.
EIN: 46-3383293
Foundation Overview
Based in Jacksonville, FL, Scott R Mackenzie Foundation Inc has awarded 42 grants totaling $8,248,047 to organizations in Florida, New York and 5 other states across the US. Individual grants range from $9,763 to $450,000, with a median award of $150,000.
Latest Tax Year
2024
Total Giving (all years)
$8,248,047
Total Assets
$24,535,320
Median Grant (all grants)
$150,000
Latest Form 990-PF Snapshot
Total Grants
5
Median Grant
$149,345
% No Significant Change
-4%
(vs previous year)
Data extracted from IRS Form 990-PF filings. Last filing year:
February 2026
Foundation Intelligence
Advanced analytics and strategic insights to help nonprofit organizations assess grant opportunities and optimize their application strategies
New Applicant Friendliness
Balanced Approach: 40%
2 of 5 recipients (40%) were new grantees. Foundation maintains loyal partnerships while remaining open to qualified new applicants with strong proposals.
Geographic Focus
Florida
50% of grants are awarded in Florida, with additional funding distributed across 6 other locations. The foundation balances regional focus with broader geographic diversity. Within Florida, funding concentrates in Gainesville (67%), Jacksonville (24%), Miami (5%).
Funding Trajectory
-3%
Stable funding levels with 3% change over 8 years indicate consistent grant-making capacity and predictable philanthropic resources. This stability suggests reliable ongoing funding opportunities.
Program Areas
Healthcare + 3 others
Diversified giving across multiple program areas with primary emphasis on healthcare (76%). This broad approach suggests openness to various causes and innovative cross-sector solutions.
Where is The Money Going?
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Grants & Funding
Analyzing past grantees provides valuable insights into Scott R Mackenzie Foundation Inc's funding preferences, organizational priorities, and grant making patterns. This historical data helps potential applicants understand the foundation's strategic focus and identify successful funding approaches.
| Name | Amount | Location | Purpose | Year |
|---|---|---|---|---|
| Hmh Hospitals Corporation | $150,000 | Edison, NJ, US | Year 2 Funding - This Project Seeks To Focus On Quantifying Selective Pressures Applied By Nucleotide Depletion And Genomic Stress In Order To Dissect The Evolutionary Dynamics Of Cancer Cells Across Multiple Tumor Types, Including Leukemia, Lymphoma, Myeloma, Colorectal Cancer, Melanoma, And Retinoblastoma. | 2024 |
| Mount Desert Island Biological Laboratory | $450,000 | Bar Harbor, ME, US | This Project Seeks To Continue The Project Awarded In 2022 To Establish A Novel Treatment Strategy For Diabetic Kidney Disease. Previous Support From The Mackenzie Foundation Is Allowing Mdi Bio Lab To Understand The Structure And Functional Parts Of The Hpa2 Molecule And Establish A Baseline From Which To Fully Understand Its Function. Based On This Ongoing Work, Mdi Bio Lab Now Seeks To Investigate The Effect Of Diabetes In A Model Organism Of Aging (African Turquoise Killifish). Simultaneously, Mdi Bio Lab Also Proposes To Use This Model To Study The Loss Of Peritubular Capillaries Observed During Kidney Aging. | 2024 |
| University Of Florida Foundation | $125,000 | Gainesville, FL, US | Year 2 Funding - This Project Seeks To Define Treatment Regimens Of Blood Thinning Medications Associated With Reduced Risk Of Recurrent Heart Attacks, Which May Include The Use Of The More Potent Blood Thinner Ticagrelor Also In Patients With Stable Coronary Artery Disease. | 2024 |
| University Of Florida Foundation | $149,345 | Gainesville, FL, US | Year 2 Funding - This Project Seeks To Identify Dependencies Of Tumor Cells In Deep Margins By Performing Single-cell Sequencing On Larger Cohort Of Tumors The Grantee Collected (N=28) And Testing Their Findings In Model Systems. Thus, The Study Would Open New Avenues For Therapies Targeting Specific Traits Within Tumor Cells Driving Recurrence, And For Improved Strategies Releasing The Host Immune System Against Glioblastoma. | 2024 |
| University Of Miami College Of Medicine | $86,571 | Coral Gables, FL, US | Year 2 Funding - This Project Seeks To Utilize Generative Adversarial Network (Gan) Models To Create High-quality Synthetic Images Representing Various Prostate Cancer (Pca) Grades. These Images Will Be Tailored To Account For The Morphological And Genomic Granularity Associated With Each Gleason Grade While Requiring Significantly Smaller Training Data Samples. Preliminary Data Indicates That This Approach Considerably Enhances Ai Models' Prognostic Capabilities For Pca. | 2024 |
| Mayo Clinic | $32,506 | Jacksonville, FL, US | The Benefactor Desires That Grantee Shall Use This Gift To Support The Tapestry Study. | 2022 |
| Mount Desert Island Biological Laboratory | $450,000 | Bar Harbor, ME, US | The Benefactor Desires That Grantee Shall Use The Gift To Seek To Prevent Organ Complications In Diabetic Patients. High Glucose Levels Lead To The Pathological Changes In The Vasculature Of Different Organs Such As The Heart, Kidney, Eye And Peripheral Circulation. The Focus Is The Microcirculation Of The Kidney. The Endothelial Cell Surface Is Covered With A Layer Of Glycocalyx. The Glycocalyx Is Very Important For The Health Of The Vascular Wall And Regulates Central Mechanisms Such As Metabolism, Inflammation, Blood Pressure, Etc. We Will Test The Hypothesis That Recombinant Hpa2 Ameliorates Diabetic Nephropathy By Maintaining A Functional Heparan Sulfate Glycocalyx On Endothelial Cells And Monocytes. This Is A Continuation Of The Project Funded In 2021. | 2022 |
| University Of Arizona | $174,994 | Tucson, AZ, US | The Benefactor Desires That Grantee Shall Use The Gift To Seek To Improve The Diagnosis And Treatment Of Atrial Fibrillation. Todevelop Patient-specific Targeted Next-generation Gene Sequencing For Predicting And Diagnosing Atrial Fibrillation And Establish A Patient-specific Stem Cell Platform For Developing Precision Medicine Based Treatments. | 2022 |
| University Of Florida Foundation | $57,500 | Gainesville, FL, US | The Benefactor Desires That Grantee Shall Use The Gift To Seek To Test Genetic Associations With Children's Response To Albuterol And Begin A Longitudinal Pediatric Asthma Registry Combining Clinical And Genomic Data. | 2022 |
| The Jackson Laboratory | $135,000 | Bar Harbor, ME, US | The Benefactor Desires That Grantee Shall Use The Gift To Investigate Aging-related Rna Splicing Alterations To Reveal Novel Biomarkers For Quantifying Breast Cancer Risk And New Targets For Treating Breast Cancer. | 2022 |
| Cincinnati Cancer Foundation Inc | $350,000 | Cincinnati, OH, US | The Benefactor Desires That Grantee Shall Use The Gift To Establish The Advancing Precision Oncology Center ("Apoc"), Whose Purpose Is To Enable Patient Access To A Wide Range Of Ngs Testing Intended To Facilitate Early Detection, Better Outcomes, And Better Possibilities For Cancer Cures Through Earlier Detection And Intervention. | 2022 |
| Mayo Clinic | $9,763 | Jacksonville, FL, US | The Benefactor Desires That Grantee Shall Use This Gift To Support The Tapestry Study. | 2021 |
| University Of Florida Foundation | $150,000 | Gainesville, FL, US | The Benefactor Desires That Grantee Shall Use The Gift To Broaden The Discovery Of New Pancreatic Cancer Biomarkers Through Genomic Sequencing. By Sequencing Tumor And Normal Samples From Our Patients, We Can Determine Novel Cancer Drivers Including Mutations, Fusions, And Gene Expression Alterations That Drive These Cancers. New Biomarkers Will Introduce New Potential Targets For Treatment And Early Detections. | 2021 |
| University Of Florida Foundation | $125,000 | Gainesville, FL, US | The Benefactor Desires That Grantee Shall Use The Gift To Assess Potential Drug Interactions Between Cangrelor And Novel P2y12 Inhibitors And Evaluate The Impact Of Receptor Expression On Their Findings. | 2021 |
| Israel Cancer Research Fund | $148,500 | New York, NY, US | The Benefactor Desires That Grantee Shall Use The Gift To Ask How Dna Repair Is Orchestrated Despite The Packaging Of Dna Into Chromatin. Swi/snf Proteins Establish And Maintain Chromatin Structure. Subunits Of Swi/snf Proteins Are Mutated In 20% Of Cancers, Implicating Them In Carcinogenesis, And Making Them Attractive Candidates For Cancer-specific And Selective Therapies. Dr. Adar Expects To Establish That Swi/snf Remodelers Facilitate Specific Steps In Nucleotide Excision Repair (ner) In Chromatin Templates, And That Cancer Associated Mutants Are Deficient In This Function. This New Understanding Of Swi/snf Functions Can Then Be Leveraged To Design New Cancer Diagnostics And Chemotherapeutics. | 2021 |
| Mount Desert Island Biological Laboratory | $400,000 | Bar Harbor, ME, US | The Benefactor Desires That Grantee Shall Use The Gift To Prevent Organ Complications In Diabetic Patients. High Glucose Levels Lead To The Pathalogical Changes In The Vasculature Of Different Organs Such As The Heart, Kidney, Eye And Peripheral Circulation. The Focus Is The Microcirculation Of The Kidney. The Endothelial Cell Surface Is Covered With A Layer Of Glycocalyx. The Glycocalyx Is Very Important For The Health Of The Vascular Wall And Regulates Central Mechanisms Such As Metabolism, Inflammation, Blood Pressure, Etc. We Will Test The Hypothesis That Recombinant Hpa2 Ameliorates Diabetic Nephropathy By Maintaining A Functional Heparan Sulfate Glycocalyx On Endothelial Cells And Monocytes. | 2021 |
| University Of Arizona | $175,006 | Tucson, AZ, US | The Benefactor Desires That Grantee Shall Use The Gift To Improve The Diagnosis And Treatment Of Atrial Fibrillation. To Develop Patient-specific Targeted Next-generation Gene Sequencing For Predicting And Diagnosing Atrial Fibrillation And Establish A Patient-specific Stem Cell Platform For Developing Precision Medicine Based Treatments. | 2021 |
| Mayo Clinic | $9,763 | Jacksonville, FL, US | The Benefactor Desires That Grantee Shall Use This Gift To Support The Tapestry Study. | 2021 |
| University Of Florida Foundation | $150,000 | Gainesville, FL, US | The Benefactor Desires That Grantee Shall Use The Gift To Broaden The Discovery Of New Pancreatic Cancer Biomarkers Through Genomic Sequencing. By Sequencing Tumor And Normal Samples From Our Patients, We Can Determine Novel Cancer Drivers Including Mutations, Fusions, And Gene Expression Alterations That Drive These Cancers. New Biomarkers Will Introduce New Potential Targets For Treatment And Early Detections. | 2021 |
| University Of Florida Foundation | $125,000 | Gainesville, FL, US | The Benefactor Desires That Grantee Shall Use The Gift To Assess Potential Drug Interactions Between Cangrelor And Novel P2y12 Inhibitors And Evaluate The Impact Of Receptor Expression On Their Findings. | 2021 |
| Israel Cancer Research Fund | $148,500 | New York, NY, US | The Benefactor Desires That Grantee Shall Use The Gift To Ask How Dna Repair Is Orchestrated Despite The Packaging Of Dna Into Chromatin. Swi/snf Proteins Establish And Maintain Chromatin Structure. Subunits Of Swi/snf Proteins Are Mutated In 20% Of Cancers, Implicating Them In Carcinogenesis, And Making Them Attractive Candidates For Cancer-specific And Selective Therapies. Dr. Adar Expects To Establish That Swi/snf Remodelers Facilitate Specific Steps In Nucleotide Excision Repair (Ner) In Chromatin Templates, And That Cancer Associated Mutants Are Deficient In This Function. This New Understanding Of Swi/snf Functions Can Then Be Leveraged To Design New Cancer Diagnostics And Chemotherapeutics. | 2021 |
| Mount Desert Island Biological Laboratory | $400,000 | Bar Harbor, ME, US | The Benefactor Desires That Grantee Shall Use The Gift To Prevent Organ Complications In Diabetic Patients. High Glucose Levels Lead To The Pathalogical Changes In The Vasculature Of Different Organs Such As The Heart, Kidney, Eye And Peripheral Circulation. The Focus Is The Microcirculation Of The Kidney. The Endothelial Cell Surface Is Covered With A Layer Of Glycocalyx. The Glycocalyx Is Very Important For The Health Of The Vascular Wall And Regulates Central Mechanisms Such As Metabolism, Inflammation, Blood Pressure, Etc. We Will Test The Hypothesis That Recombinant Hpa2 Ameliorates Diabetic Nephropathy By Maintaining A Functional Heparan Sulfate Glycocalyx On Endothelial Cells And Monocytes. | 2021 |
| University Of Arizona | $175,006 | Tucson, AZ, US | The Benefactor Desires That Grantee Shall Use The Gift To Improve The Diagnosis And Treatment Of Atrial Fibrillation. To Develop Patient-specific Targeted Next-generation Gene Sequencing For Predicting And Diagnosing Atrial Fibrillation And Establish A Patient-specific Stem Cell Platform For Developing Precision Medicine Based Treatments. | 2021 |
| Mayo Clinic | $60,934 | Jacksonville, FL, US | The Benefactor Desires That Grantee Shall Use The Gift To Support The Tapestry Study. | 2020 |
| Florida International | $350,000 | Miami, FL, US | The Benefactor Desires That Grantee Shall Use The Funds To Support Characherizing Sarcoma Mutations With Matching Drugs And Appropriate Targeted Treatments By Implementing A Combined Functional Drug Screening And Genomics Platform And Selecting Clinically Approved Compounds To Offer Advanced Sarcoma Patients The Safest Possible Chance Of Achieving Remissions And Ultimately Curing Their Disease. | 2020 |
| University Of North Florida | $128,449 | Jacksonville, FL, US | The Benefactor Desires That The Grantee Shall Use The Gift To Support A 16 Week Study On The Effect Of Fermented Foods On The Gut Microbiota For Prevention Of Cardiovascular Disease To Help Reduce The Mortality Rate Of Cardiovascular Disease. | 2020 |
| University Of Florida Foundation | $150,000 | Gainesville, FL, US | The Benefactor Desires That Grantee Shall Use The Gift To Support The Offering Of Genetic Testing And Related Downstream Services To All Patients Diagnosed With Pancreatic Cancer At Uf Health. | 2020 |
| University Of Florida Foundation | $125,000 | Gainesville, FL, US | The Benefactor Desires That Grantee Shall Use The Gift To Support Advancing The Understanding Of Therapeutic Approaches Aimed To Improve Outcomes In A High-risk Patient Population Representing A Pandemic Health Care Problem Such As Those With Diabetes Mellitus And Chronic Kidhey Disease. | 2020 |
| University Of Florida Foundation | $125,000 | Gainesville, FL, US | The Benefactor Desires That Grantee Shall Use The Gift To Support Athe Assessment Of The Impact Of Timing Of Administration Of Potent Oral P2y12 Inhibitors (ticagrelor And Prasugrel) On The Pharmacokinetic (pk)/ Pharmacodynamic (pd) Effects After Switching From Intravenous Cangrelor Infusion And How Levels Of P2y12 Reseptor Gene Expresiion Can Affect Such Response Profiles. | 2020 |
| Mdi Biological Laboratory | $336,691 | Bar Harbor, ME, US | The Benefactor Desires That Grantee Shall Use The Funds To Support Research To Define Both A Mechanism Of Action And A More Effective Treatment Paradigm In Molecular Stimulation Of The Natural Repair Processes In The Heart And Other Tissues. | 2018 |
| The Jackson Laboratory | $330,000 | Farmington, CT, US | The Benefactor Desires That Grantee Shall Use The Funds To Support The Identification Of A Potentially Curative Regimen For Tandem Duplicator Phenotype Triple Negative Breast Cancer To Be Tested In A Panel Of Human Triple Negative Breast Cancer Tumors Growing In Mice. | 2018 |
| The Jackson Laboratory | $280,000 | Farmington, CT, US | The Benefactor Desires That Grantee Shall Use The Funds To Support A Study Where Patients Will Be Recruited To Contribute Tumor And Gut Microbe Samples For Sequencing To Identify Involved Microbes, And Will Also Develop A Mouse Model For Testing Candidates That Will Have Broad Utility Beyond The Scope Of This Specific Project. | 2018 |
| Mdi Biological Laboratory | $350,000 | Bar Harbor, ME, US | The Benefactor Desires That Grantee Shall Use The Funds To Support Research To Define Both A Mechanism Of Action And A More Effective Treatment Paradigm In Molecular Stimulation Of The Natural Repair Processes In The Heart And Other Tissues. | 2017 |
| The Jackson Laboratory | $282,000 | Farmington, CT, US | The Benefactor Desires That Grantee Shall Use The Funds To Support The Identification Of A Potentially Curative Regimen For Tandem Duplicator Phenotype Triple Negative Breast Cancer To Be Tested In A Panel Of Human Triple Negative Breast Cancer Tumors Growing In Mice. | 2017 |
| The Jackson Laboratory | $307,500 | Farmington, CT, US | The Benefactor Desires That Grantee Shall Use The Funds To Support A Study Where Patients Will Be Recruited To Contribute Tumor And Gut Microbe Samples For Sequencing To Identify Involved Microbes, And Will Also Develop A Mouse Model For Testing Candidates That Will Have Broad Utility Beyond The Scope Of This Specific Project. | 2017 |
| Uf Foundation | $125,000 | Gainesville, FL, US | The Benefactor Desires That Grantee Shall Use The Funds To Support The Proposed Platelet Inhibitory Profiles Of Prasugrel Versus Ticagrelor In Patients With Vyp2c19 Loss-of-function Genotypes Undergoing Coronary Intervention Study. | 2017 |
| Uf Foundation | $125,703 | Gainesville, FL, US | The Benefactor Desires That Grantee Shall Use The Funds To Support The Development And Characterization Of A New Mechanism In Mice With The Potential To Reverse The Scarring Process In The Diabetic Kidney. | 2017 |
| Mdi Biological Laboratory | $197,425 | Bar Harbor, ME, US | The Benefactor Desires That Grantee Shall Use The Funds To Support Research To Define Both A Mechanism Of Action And A More Effective Treatment Paradigm In Molecular Stimulation Of The Natural Repair Processes In The Heart And Other Tissues. | 2016 |
| Uf Health College Of Medicine | $124,297 | Gainesville, FL, US | The Benefactor Desires That Grantee Shall Use The Funds To Support The Development And Characterization Of A New Mechanism In Mice With The Potential To Reverse The Scarring Process In The Diabetic Kidney. | 2016 |
| Uf Health College Of Medicine | $125,000 | Gainesville, FL, US | The Benefactor Desires That Grantee Shall Use The Funds To Support The Proposed Platelet Inhibitory Profiles Of Prasugrel Versus Ticagrelor In Patients With Vyp2c19 Loss-of-function Genotypes Undergoing Coronary Intervention Study. | 2016 |
| The Jackson Laboratory | $197,594 | Farmington, CT, US | The Benefactor Desires That Grantee Shall Use The Funds To Support The Identification Of A Potentially Curative Regimen For Tandem Duplicator Phenotype Triple Negative Breast Cancer To Be Tested In A Panel Of Human Triple Negative Breast Cancer Tumors Growing In Mice. | 2016 |
| The Jackson Laboratory | $350,000 | Farmington, CT, US | The Benefactor Desires That Grantee Shall Use The Funds To Support A Study Where Patients Will Be Recruited To Contribute Tumor And Gut Microbe Samples For Sequencing To Identify Involved Microbes, And Will Also Develop A Mouse Model For Testing Candidates That Will Have Broad Utility Beyond The Scope Of This Specific Project. | 2016 |
Foundations Similar to Scott R Mackenzie Foundation Inc
Discover 5 foundations with comparable assets ($22,077,670-$26,513,838), similar grant patterns, and geographic focus in FL that may also align with your organization's funding needs and grant seeking strategy.
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Cj Robinson Residuary - Tes Tr
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Contact Information
Official contact details for Scott R Mackenzie Foundation Inc as registered with the IRS. These details are essential for grant applications, correspondence, and due diligence processes.
| EIN | 46-3383293 |
| Website | http://www.scottrmackenziefoundation.com |
| Address | 2518 PARK ST Jacksonville, FL 32204-4518 |
Key People (6)
Board members, trustees, and key staff who oversee Scott R Mackenzie Foundation Inc's grant making decisions and strategic direction. Understanding leadership composition can provide insights into foundation priorities and potential networking opportunities.
| Director | Scott R Mackenzie |
|---|---|
| Director | Melinda A Mackenzie |
| Director | Lawrence B Mackenzie |
| Director | Julian Fant |
| Exec. Director | Carolyn Tucker |
Forms 990-PF
IRS Form 990-PF filings provide comprehensive financial information, grant details, and operational data. These documents are essential resources for understanding foundation capacity, giving patterns, and strategic priorities.
Form 990-PF Research Tips
- Review Part XV for detailed grant recipient information and funding purposes
- Check Part I for total assets, annual giving amounts, and payout requirements
- Examine Part VIII for key personnel compensation and board structure
- Look for trends across multiple years to understand giving patterns
About This Foundation Profile
This comprehensive foundation profile for Scott R Mackenzie Foundation Inc is powered by Grant Bay's advanced foundation research platform. Our system analyzes IRS Form 990-PF filings, grant histories, and philanthropic patterns to provide nonprofit organizations with actionable intelligence for grant seeking success.
Data Sources & Accuracy
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Data Currency: Last updated
February 2026
based on IRS Form 990-PF filings. Foundation information reflects most recent available tax year data.